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More accurately, in a press release for an article coming from our lab group….

Here’s the link to the article:

Paul D. Blischak, Aaron J. Wenzel, and Andrea D. Wolfe. 2014. Gene prediction and annotation in Penstemon (Plantaginaceae): A workflow for marker development from extremely low-coverage genome sequencing. Applications in Plant Sciences 2(12): 1400044. doi:10.3732/apps.1400044.

Here’s the link to the press release:


One pipeline that combines many gene-finding tools

Researchers develop a MAKER2 workflow for phylogenetic marker design with low-coverage genomic data


Reconstructing relationships among plant species is critical for a better understanding of fundamental aspects of plant biology, such as genome evolution, speciation, pollination biology, and many other areas.

However, evolutionary relationships within many plant groups have been difficult to reconstruct, often due to factors such as rapid diversification, hybridization, and incomplete lineage sorting. In such cases, large data sets including numerous genetic markers from both the nuclear and organellar genomes are necessary to accurately determine relationships. But developing numerous genetic markers for phylogenetic study is often difficult in the absence of extensive genomic resources, which are available for only a small portion of plant species.

Fortunately, advances in sequencing technologies are helping researchers develop large data sets even in challenging genomes. One example of this is the MAKER2 Annotation Pipeline, a free and open-source pipeline that combines a variety of bioinformatic tools for genome analysis, better known as “genome annotation.”

Using MAKER2, researchers at Ohio State University have developed a workflow that identifies numerous genetic markers for phylogenetic study from limited genomic data. The approach, published in a recent issue of Applications in Plant Sciences, is exemplified using the flowering plant genus Penstemon (Plantaginaceae), whose phylogeny has been difficult to resolve due to its recent, rapid radiation.

…. the article continues – check out the link…